Re: [Pediatric_sedation] intranasal dexmedetomidine and mucosalatomization device

["Connors, Mick Dr." <MConnors@etch.com>]

Curious if folks could comment on what they feel the benefits of intranasal vs buccal precedex???
 
 
Mick Connors

________________________________

From: pediatric_sedation-bounces@listserve.com on behalf of joycephil@aol.com
Sent: Mon 6/22/2009 4:41 PM
To: pediatric_sedation@listserve.com
Subject: [Pediatric_sedation] intranasal dexmedetomidine and mucosalatomization device



We have used intranasal dex as both a premed and as a sole sedative for
CT.
We administer it using the M.A.D. (mucosal atomization device) also
known as the "marshmallow" which is distributed by Wolfe Tory. It
produces a fine mist with maximal mucosal coverage. We have used doses
 from 2-5 mcg/kg of precedex intranasally as a premed particularly in
children with autism.  The precedex is odorless and painless and the
administration is quick. Onset is in 20 minutes with maximal effect in
about 40 minutes. Children are generally sleepy for about an hour and a
half. We have seen no hemodynamic changes using these doses
and this route of administration.  I have on occasion given a second
nasal dose without problem.

Joyce Phillips, MD, FAAP
University of New Mexico
Department of Anesthesiology
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