Re: [Pediatric_sedation] intranasal dexmedetomidine and mucosalatomization device

["Lubisch, Nina" <Nlubisch@browardhealth.org>]

Dr Phillips,
Do you have a wrtitten protocol for your intransal precedex and do you
have some references available. How many cases and what type of
procedures are you using IN Dex for? I would like to speak with you by
phone if and when your are able.
Thank you!
Nina b. Lubisch, ARNP
Chris Evert Childrens Hospital,
Broward County, Fl 

-----Original Message-----
From: pediatric_sedation-bounces@listserve.com
[mailto:pediatric_sedation-bounces@listserve.com] On Behalf Of
joycephil@aol.com
Sent: Monday, June 22, 2009 4:41 PM
To: pediatric_sedation@listserve.com
Subject: [Pediatric_sedation] intranasal dexmedetomidine and
mucosalatomization device

We have used intranasal dex as both a premed and as a sole sedative for
CT.
We administer it using the M.A.D. (mucosal atomization device) also
known as the "marshmallow" which is distributed by Wolfe Tory. It
produces a fine mist with maximal mucosal coverage. We have used doses
from 2-5 mcg/kg of precedex intranasally as a premed particularly in
children with autism.  The precedex is odorless and painless and the
administration is quick. Onset is in 20 minutes with maximal effect in
about 40 minutes. Children are generally sleepy for about an hour and a
half. We have seen no hemodynamic changes using these doses and this
route of administration.  I have on occasion given a second nasal dose
without problem.

Joyce Phillips, MD, FAAP
University of New Mexico
Department of Anesthesiology
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