Re: [Pediatric_sedation] intranasal dexmedetomidine andmucosalatomization device

["Lubisch, Nina" <Nlubisch@browardhealth.org>]

Mick,
In response to your question of benefits of IN verses buccal: I have
found that the buccal has more hemodynamic changes than does IN which in
our small population has shown. I do see that the length of time to fall
asleep is longer for IN but the recovery is so fast in comparison.
Nina 

-----Original Message-----
From: pediatric_sedation-bounces@listserve.com
[mailto:pediatric_sedation-bounces@listserve.com] On Behalf Of Connors,
Mick Dr.
Sent: Tuesday, June 23, 2009 9:40 AM
To: Pediatric Sedation Discussion
Subject: Re: [Pediatric_sedation] intranasal dexmedetomidine
andmucosalatomization device

Curious if folks could comment on what they feel the benefits of
intranasal vs buccal precedex???

 

 

Mick Connors



________________________________



From: pediatric_sedation-bounces@listserve.com on behalf of
joycephil@aol.com

Sent: Mon 6/22/2009 4:41 PM

To: pediatric_sedation@listserve.com

Subject: [Pediatric_sedation] intranasal dexmedetomidine and
mucosalatomization device







We have used intranasal dex as both a premed and as a sole sedative for

CT.

We administer it using the M.A.D. (mucosal atomization device) also

known as the "marshmallow" which is distributed by Wolfe Tory. It

produces a fine mist with maximal mucosal coverage. We have used doses

 from 2-5 mcg/kg of precedex intranasally as a premed particularly in

children with autism.  The precedex is odorless and painless and the

administration is quick. Onset is in 20 minutes with maximal effect in

about 40 minutes. Children are generally sleepy for about an hour and a

half. We have seen no hemodynamic changes using these doses

and this route of administration.  I have on occasion given a second

nasal dose without problem.



Joyce Phillips, MD, FAAP

University of New Mexico

Department of Anesthesiology

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